Saturday, March 19, 2011

Fruit Protein: Another cause of FPIES

I found this article: Fruit Protein; Another cause of FPIES while reading through the previous article I posted about (New FPIES study from Isreal).  It, of course, grabbed my attention because of the commonality of so many kids in the support groups having problems with fruit proteins as much as the common triggers.   

The article describes the documented case of an infant who had a positive, classic reaction to a fruit mixture.   The confirmation was made when the fruits were stopped and symptoms subsided, and then reintroduction elicited an FPIES trigger response.

The concluding paragraph in the article is intriguing for more research, as it spells out some possible connections with fruits due to their plant tissue structures...."The present study clearly shows that also proteins contained in fruits can be responsible of FPIES, which may have a prolonged course. Plant tissues contain thousands of different proteins (5) and it is difficult to identify the culprit antigens. Common related proteins such as nonspecific lipid transfer proteins, which are resistant to proteolysis and thermal treatment, and/or pathogenesis-related proteins might be the antigens responsible for the reaction."

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